Wouldnt be my first choice for deer, but if I had to put meat on the table and that was all I had, A couple companies, Federal I think load specific ammo for deer while not ideal would be the best you can do, with the amount of money and expense involved in all the other aspects of deer hunting probably better off using enough gun, With a perect shot perfect angle it'll do the job but anyone who has spent any time in the deer woods knows how quickly things can screw up. The deer allways walks up behind your right shoulder.